
hmgbiotech HM-120
HMGB 1是細(xì)胞核的一個(gè)組成部分,在基因組的組織和表達(dá)中具有多種功能。HMG生物技術(shù)SRL為活躍在這一領(lǐng)域的其他研究人員和公司提供試劑、服務(wù)和想法。它還有助于實(shí)驗(yàn)室開(kāi)發(fā)分析和試劑。
hmgbiotech  DISULFIDE HMGB1說(shuō)明書(shū)
hmgbiotech HM-120
HMGB1是一種核蛋白,其由壞死細(xì)胞被動(dòng)釋放,由凋亡細(xì)胞保留,并由炎癥細(xì)胞主動(dòng)分泌(Dumitriu等人,HMGB1:從內(nèi)部引導(dǎo)免疫。Trends Immunol 2005,26:381-7)。HMGB1對(duì)生命至關(guān)重要:HMGB1基因敲除小鼠出生后不久死亡。
HMGB1作為運(yùn)動(dòng)細(xì)胞的化學(xué)引誘劑和細(xì)胞因子的誘導(dǎo)劑的兩種不同活性被歸因于不同的生物化學(xué)形式。還原的HMGB1(具有化學(xué)引誘活性的形式)被還原;二硫化物HMGB1包含C23和C45之間的二硫鍵(完整注釋:HMGB1C23-C45C106h–Antoine J.等人(2014)。Mol-Med)。
二硫化物HMGB1可誘導(dǎo)單核細(xì)胞和其他炎癥細(xì)胞產(chǎn)生細(xì)胞因子和趨化因子(Venereau等人,2012)。
在結(jié)構(gòu)上,二硫化物HMGB1在半胱氨酸殘基23和45與還原的半胱氨酸殘基106之間具有二硫鍵。測(cè)試二硫化物HMGB1刺激細(xì)胞因子的能力
HMGBiotech公司熱銷產(chǎn)品
| 產(chǎn)品名稱 | 貨號(hào) | 
| 100 ug Fully reduced HMGB1, LPS free | HM-115 | 
| 50 ug Fully reduced HMGB1, LPS free | HM-116 | 
| 100 ug Disulfide HMGB1, LPS free | HM-121 | 
| 100 ug BoxA from HMGB1, LPS-free and tested in migration assay | HM-012 | 
| 50 ug Disulfide HMGB1, LPS free | HM-122 | 
| 500 ug BoxA from HMGB1, LPS-free and tested in migration assay | HM-013 | 
| 1 mg HMGB1 for biochemistry | HM-100 | 
| 2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay | HM-014 | 
| 250 ug HMGB1 biochemistry | HM-101 | 
| 25 ug BoxA from HMGB1, LPS-free and tested in migration assay | HM-011 | 
| 15 ug BoxB from HMGB1, LPS-free and tested in migration assay | HM-053 | 
| 15 ug Fully reduced HMGB1, LPS free | HM-117 | 
| 10 ug Disulfide HMGB1, LPS free | HM-123 | 
| 15 ug Non-oxidizable HMGB1, LPS free | HM-133 | 
| 250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-170 | 
| 100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-171 | 
| 50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-172 | 
| 15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-173 | 
| 50 ug HMGB1 15N labelled for Mass Spectrometry | HM-180 | 
| 5 ug HMGB1 15N labelled for Mass Spectrometry | HM-181 | 
| 2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-190 | 
| 500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-191 | 
| 100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-192 | 
| 25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-193 | 
| Control cell lysates from Hmgb1 +/+ | HM-001 | 
| Control cell lysates from Hmgb1 -/- | HM-002 | 
| 1 mg BoxB from HMGB1, LPS-free and tested in migration assay | HM-050 | 
| 250 ug BoxB from HMGB1, LPS-free and tested in migration assay | HM-051 | 
| 100 ug BoxB from HMGB1, LPS-free and tested in migration assay | HM-052 | 
| 500 ug Fully reduced HMGB1, LPS free | HM-114 | 
| 250 ug Disulfide HMGB1, LPS free | HM-120 | 
| 500 ug Non-oxidizable HMGB1, LPS free | HM-130 | 
| 100 ug Non-oxidizable HMGB1, LPS free | HM-131 | 
| 50 ug Non-oxidizable HMGB1, LPS free | HM-132 | 
| 500 ug HMGB2, LPS-free and tested in migration assay | HM-151 | 
| 100 ug HMGB2, LPS-free and tested in migration assay | HM-152 | 
| 50 ug HMGB2, LPS-free and tested in migration assay | HM-153 | 
| Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells | HM-201 | 
| Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells | HM-221 | 
| Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and | HM-223 | 
| HMGB1 Isoforms Kit - Test size | HM-030 | 
| Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells | HM-251 | 
| HMGB1 Isoforms Kit - Regular size | HM-031 | 
| 20 ug p-mHMG1 | HM-300 | 
| 50 ug Terminally oxidized HMGB1, LPS free | HM-062 | 
| 20 ug p-mHMG1tag | HM-301 | 
| 100 ug Terminally oxidized HMGB1, LPS free | HM-061 | 
| 20 ug pEGFP-HMGB1 | HM-302 | 
| 250 ug Terminally oxidized HMGB1, LPS free | HM-060 | 
| 20 ug pcDNA/FL-RAGE plasmid | HM-310 | 
 地址:上海浦東川沙鎮(zhèn)川沙路6619號(hào)上海起發(fā)實(shí)驗(yàn)試劑有限公司
地址:上海浦東川沙鎮(zhèn)川沙路6619號(hào)上海起發(fā)實(shí)驗(yàn)試劑有限公司 郵箱:xs1@78bio.com
郵箱:xs1@78bio.com 傳真:021-50724961
傳真:021-50724961
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